If the buds are much bigger than others on the same plants, it may well be big bud. If there are only a few, pick them off and destroy them. If they're old plants which have been neglected, it may pay you in the long run to cut them down and let them regrow; old wood will produce very little, and all new should give you a bumper crop next year. Similarly, if they are covered with big bud, cut them right down and burn the branches. Make sure it really is big bud first!